lettuce
Vegetables
Is lettuce high in tyramine?
Find out whether lettuce is high or low in tyramine, see its exact rating, and check its FODMAP, salicylate, oxalate and diet compatibility all in one place.
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Sensitivity notes
Why tyramine food checker matters
Tyramine is an amino acid that forms when proteins break down. It's found in aged, fermented, or spoiled foods. For people taking MAO inhibitors or those with tyramine sensitivity, it can cause headaches, elevated blood pressure, and other reactions.
- Choose fresh over aged, fermented, or preserved foods
- Eat protein foods fresh and store properly
- Be especially careful if taking MAO inhibitor medications
Triggers
Diets
Serving size, prep, and portion notes for lettuce
Lettuce is a safe base green, clean across nearly every trigger: low histamine, low salicylate, gluten free, and importantly low in oxalate, unlike spinach, which is very high in oxalate. That makes lettuce a reliable salad base when spinach and other leafy greens are off the table. Two small notes keep it honest: it carries a modest FODMAP load in very large volumes, and its nickel content is borderline rather than negligible.
Watch for
Low oxalate, in clear contrast to spinach, which is high oxalate: swapping spinach for lettuce is a common move on a low-oxalate diet / Moderate FODMAP only in large volumes, so a normal side salad is fine while a huge bowl can add up for a sensitive gut / Nickel sits at a borderline level, worth noting if you have a strict systemic nickel allergy but not a concern for most people
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Tyramine Guide
Everything you need to know about tyramine sensitivity and smart food choices.
Tyramine is an amino acid that forms when proteins break down. It's found in aged, fermented, or spoiled foods. For people taking MAO inhibitors or those with tyramine sensitivity, it can cause headaches, elevated blood pressure, and other reactions.
Sensitivity varies widely. What triggers one person may be fine for another. Track your reactions to find your personal threshold.
These foods are generally well-tolerated for Tyramine sensitivity:
View all safe options
These foods are high in tyramine and may trigger symptoms:
View full list
If you're sensitive to Tyramine, consider these strategies:
- 1Choose fresh over aged, fermented, or preserved foods
- 2Eat protein foods fresh and store properly
- 3Be especially careful if taking MAO inhibitor medications
- 4Common high-tyramine foods include aged cheese, cured meats, and soy sauce
- 5Ripeness affects tyramine - choose less ripe fruits
Pro tip: Keep a food diary to track your reactions. The Triggerbites app makes this easy with automatic pattern detection.
Want personalized tracking?
Download Triggerbites to log meals, track symptoms, and discover your unique triggers.
Get the AppFAQ
Is lettuce high in Tyramine?
Tyramine: low signal for most people.
Can I still eat lettuce if I'm sensitive to Tyramine?
Usually fine in normal portions.
What else should I check?
Check FODMAPs, Nickel, and FODMAPs next for a fuller picture.