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black seed
Herbs & Spices
Is black seed high in tyramine?
Is black seed high or low in tyramine? See its exact rating, how much counts as a portion, and its FODMAP, salicylate, oxalate and diet compatibility in one place.
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Sensitivity notes
Why tyramine food checker matters
Tyramine is an amino acid that forms when proteins break down. It's found in aged, fermented, or spoiled foods. For people taking MAO inhibitors or those with tyramine sensitivity, it can cause headaches, elevated blood pressure, and other reactions.
- Choose fresh over aged, fermented, or preserved foods
- Eat protein foods fresh and store properly
- Be especially careful if taking MAO inhibitor medications
- Common high-tyramine foods include aged cheese, cured meats, and soy sauce
- Ripeness affects tyramine - choose less ripe fruits
Sensitivities
What black seed contains
FODMAPs
Histamine & Amines
Plant compounds
Irritants
Additives
Allergens
Diet fit
Where black seed fits
Therapeutic diets
Lifestyle diets
Religious diets
What to know about black seed
Black seed is Nigella sativa, the small matte-black seed scattered over naan and Turkish bread and stirred into Bengali panch phoron. As a spice it grades clean across the board here, with no histamine, no tyramine, no free glutamate, no sulfites, no salicylate flag and no FODMAP load. The reason it needs a page at all is that most people meeting it now are not meeting a spice. They are taking black seed oil capsules or a spoon of cold-pressed oil standardised for thymoquinone, and that is a daily dose orders of magnitude larger than anything you would sprinkle on bread. Almost every reported side effect and drug interaction belongs to the supplement, not the seed.
Watch for
- The culinary dose and the supplement dose are not the same exposure.A pinch of seed on flatbread is a fraction of a gram, while black seed oil regimens run one to three grams a day standardised for thymoquinone, the compound that makes up roughly half a percent to two percent of the oil. If you started a supplement, log it as a supplement.
- At supplement doses the common complaints are gastric: bloating, nausea, loose stools and reflux.These read exactly like a new food intolerance in a diary, so a black seed oil start date is worth marking before you go hunting through your meals.
- Thymoquinone interacts with cytochrome P450 enzymes including CYP2C9, the pathway that clears warfarin, and trials consistently show modest blood-sugar and blood-pressure lowering.Stacked with an anticoagulant, a diabetes drug or a blood-pressure medication, the effects add up. Clear a black seed oil habit with whoever manages your prescriptions.
- Rash and skin hypersensitivity are the recurring non-gut reports, and contact dermatitis from black seed oil applied to skin is documented.Nigella sativa is unrelated to true cumin despite the shared name, so a cumin allergy tells you nothing about it.
- As a whole spice it grades clean on histamine, gluten, lactose, nickel, sulfites, nightshades and all FODMAP subgroups, which makes it one of the easier ways to add flavour on a restricted diet.
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Tyramine Guide
Everything you need to know about tyramine sensitivity and smart food choices.
Tyramine is an amino acid that forms when proteins break down. It's found in aged, fermented, or spoiled foods. For people taking MAO inhibitors or those with tyramine sensitivity, it can cause headaches, elevated blood pressure, and other reactions.
Sensitivity varies widely. What triggers one person may be fine for another. Track your reactions to find your personal threshold.
These foods are generally well-tolerated for Tyramine sensitivity:
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These foods are high in tyramine and may trigger symptoms:
View full list
If you're sensitive to Tyramine, consider these strategies:
- 1Choose fresh over aged, fermented, or preserved foods
- 2Eat protein foods fresh and store properly
- 3Be especially careful if taking MAO inhibitor medications
- 4Common high-tyramine foods include aged cheese, cured meats, and soy sauce
- 5Ripeness affects tyramine - choose less ripe fruits
Pro tip: Keep a food diary to track your reactions. The Triggerbites app makes this easy with automatic pattern detection.
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Get the AppFAQ
Is black seed high in Tyramine?
Tyramine: low signal for most people.
Can I still eat black seed if I'm sensitive to Tyramine?
Usually fine in normal portions.
What else should I check?
Check AIP, Low Fibre, and Gastroparesis Diet next for a fuller picture.