sake
Beverages
Is sake high in tyramine?
Is sake high or low in tyramine? See its exact rating, how much counts as a portion, and its FODMAP, salicylate, oxalate and diet compatibility in one place.
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Sensitivity notes
Why tyramine food checker matters
Tyramine is an amino acid that forms when proteins break down. It's found in aged, fermented, or spoiled foods. For people taking MAO inhibitors or those with tyramine sensitivity, it can cause headaches, elevated blood pressure, and other reactions.
- Choose fresh over aged, fermented, or preserved foods
- Eat protein foods fresh and store properly
- Be especially careful if taking MAO inhibitor medications
- Common high-tyramine foods include aged cheese, cured meats, and soy sauce
- Ripeness affects tyramine - choose less ripe fruits
Sensitivities
What sake contains
FODMAPs
Histamine & Amines
Plant compounds
Irritants
Additives
Allergens
Diet fit
Where sake fits
Therapeutic diets
Lifestyle diets
Religious diets
What to know about sake
Sake is brewed, not distilled, and that one fact explains its whole trigger profile. A spirit leaves its fermentation by-products behind in the still, which is why vodka and gin come out so clean. Sake keeps everything the koji mould and the yeast made, so it grades borderline on histamine, on histamine liberation and on tyramine, the same amine cluster that makes wine and beer hard work for a lot of people. What sake does not share with wine is sulfites. Winemakers routinely add sulfur dioxide as a preservative, while sake is normally stabilised by pasteurisation (hi-ire) instead and carries only the small amount of sulfite that fermentation produces on its own, which is why it grades borderline here against wine at the top of the scale. Sake is also gluten free, since it is made from nothing but rice, water, koji and yeast, and it grades far below wine on salicylate. The koji step is what makes sake savoury rather than merely sweet, breaking rice protein into free amino acids, and that is also why free glutamate grades borderline.
Watch for
- Borderline on all three amine measures at once (histamine, histamine liberation and tyramine), so sake is a plausible answer to why a Japanese meal ends in flushing or a headache even when the food was fresh
- Sulfite grades borderline rather than high, unlike wine, because sake is usually preserved by pasteurisation instead of added sulfur dioxide: check the label anyway, since some export bottlings do declare added sulfites
- Sweeter and cloudy nigori styles carry more residual sugar, which is why sake grades borderline on FODMAPs and excess fructose where a dry spirit grades clean
- Free glutamate grades borderline, a direct result of koji breaking down rice protein: the same reaction that gives sake its umami depth, and worth logging if glutamate is one of your triggers
- Sake is commonly 15 to 16 percent alcohol, stronger than most wine, and it arrives in small cups that get refilled by other people, so the actual dose is unusually easy to lose track of
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Tyramine Guide
Everything you need to know about tyramine sensitivity and smart food choices.
Tyramine is an amino acid that forms when proteins break down. It's found in aged, fermented, or spoiled foods. For people taking MAO inhibitors or those with tyramine sensitivity, it can cause headaches, elevated blood pressure, and other reactions.
Sensitivity varies widely. What triggers one person may be fine for another. Track your reactions to find your personal threshold.
These foods are generally well-tolerated for Tyramine sensitivity:
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These foods are high in tyramine and may trigger symptoms:
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If you're sensitive to Tyramine, consider these strategies:
- 1Choose fresh over aged, fermented, or preserved foods
- 2Eat protein foods fresh and store properly
- 3Be especially careful if taking MAO inhibitor medications
- 4Common high-tyramine foods include aged cheese, cured meats, and soy sauce
- 5Ripeness affects tyramine - choose less ripe fruits
Pro tip: Keep a food diary to track your reactions. The Triggerbites app makes this easy with automatic pattern detection.
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Get the AppFAQ
Is sake high in Tyramine?
Tyramine: moderate signal - portion size matters.
Can I still eat sake if I'm sensitive to Tyramine?
Try smaller portions and space it out.
What else should I check?
Check AIP, Reflux Diet, and Whole30 next for a fuller picture.