grapefruit
Fruit
Trigger checker for grapefruit
See grapefruit rated across every trigger — FODMAP, histamine, salicylate, oxalate, tyramine and more — plus diet compatibility, all in one quick ingredient profile.
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Compare grapefruit across criteria
Triggers
Diets
Serving size, prep, and portion notes for grapefruit
Grapefruit is more than a tart breakfast citrus. It is very high in oxalate, high in salicylates, and acts as a histamine liberator, an unusual triple for a fruit, and it is high FODMAP by volume with a moderate excess-fructose load. On top of that trigger profile, grapefruit is famous for interacting with dozens of prescription medications, an effect most everyday citrus like oranges and clementines does not share.
Watch for
Very high in oxalate, the most oxalate-heavy fruit in this group, which matters if you form calcium-oxalate kidney stones / Histamine liberator and high in salicylates, so it can set off flushing, itching, headaches or a runny nose in people sensitive to either / High FODMAP by volume, with a moderate excess-fructose load, so large servings or grapefruit juice can bring on bloating and loose stools / Contains furanocoumarins that block the CYP3A4 enzyme, so grapefruit can raise blood levels of many statins, blood-pressure and other drugs to unsafe levels; check with a pharmacist
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FAQ
What does the FODMAP rating mean for grapefruit?
High FODMAP: consider smaller servings or swap within the same group.
Is grapefruit generally well tolerated?
Oxalates (Avoid) and Histamine Liberators (High) Start with those if you react.
What should I check next?
Compare within the Fruit group.